Stubbs VC, et al. - Using the National Cancer Database (NCDB)'s large sample population, researchers explored the connection between two key social determinants of health, demographics and socioeconomic status (SES), and parotid malignancy survival rates. Between 2004 and 2012, the analytic sample consists of patients with a diagnosis of primary malignancy of the parotid gland in the NCDB. Univariable and multivariable Cox proportional hazard models were used to assess the link between overall survival rate and two key social determinants of health: demographics and SES. Fifteen thousand eight hundred fifteen cases met the criteria for inclusion. A poorer overall survival was associated with male sex and older age at diagnosis. The data presented in this work showed a significant association between important social determinants of health and overall survival rate in this national sample of patients with parotid malignancy, a rare form of cancer. The overall survival of females, Asian-Americans, Hispanics, and patients with higher education is better. Based on income level, no significant survival association was found.