Sleep duration and proteinuria progression: A population-based cohort study
American Journal of Nephrology Dec 20, 2018
Chang YC, et al. - In a total of 26,249 adults aged ≥20 years who were recruited through voluntary health examinations in Taiwan, researchers determined the impact of sleep duration on renal function. They administered questionnaire to participants to determine self-reported sleep duration. Using dipstick urine test, proteinuria was graded semi-quantitatively. They assessed proteinuria and estimated glomerular filtration rate (eGFR) in association with sleep duration. Participants were followed-up for an average of 2.62 years, during which the crude hazard ratios (HR) were reported, which were 1.92, 1.23, and 1.18 for proteinuria progression for those with sleep duration < 4, 4–6, and > 8 h vs those with sleep duration of 6–8 h (the reference group), respectively. An independent association of short sleep duration with the progression of proteinuria was suggested in this study. However, no significant difference was seen in eGFR among different sleep duration groups.
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