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Skeletonized vs pedicled internal mammary artery graft harvesting in coronary artery bypass surgery: A post hoc analysis rom the COMPASS trial

JAMA Jun 21, 2021

Lamy A, Browne A, Sheth T, et al. - Researchers examined the association of skeletonized vs pedicled harvesting of the internal mammary artery with internal mammary artery graft patency and clinical outcomes after coronary artery bypass graft (CABG) surgery. In this post hoc analysis, 1,002 patients undergoing CABG surgery in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) randomized clinical trial were assessed. Among these patients, 282 underwent skeletonized (mean [SD] age, 65.9 [8.1] years; 229 men [81.2%]; 194 White patients [68.8%]) and 720 underwent pedicled ( [71.9%]; mean [SD] age, 64.8 [7.6] years; 603 men [83.8%]; 455 White patients [63.2%]) internal mammary artery harvesting. The rate of internal mammary artery graft occlusion at 1 year was 9.6% vs 3.9% with skeletonized harvesting vs pedicled harvesting, respectively, a significant difference.

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