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Single arm phase II study of oral vitamin B12 for the treatment of musculoskeletal symptoms associated with aromatase inhibitors in women with early stage breast cancer

The Breast Journal Feb 22, 2018

Campbell A, et al. - This study assessed the effect of vitamin B12 supplements on musculoskeletal symptoms, such as pain and arthralgias induced by aromatase inhibitors (AIs), and correlated the response with serum and inflammatory biomarkers. In patients experiencing AI-related musculoskeletal symptoms, vitamin B12 reduced pain and improved quality of life, and could be a safe and cost-effective option.

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