Lavin M, et al. - Using a standardized approach to phenotypic assessment, researchers evaluated the significant gynecological bleeding in women with low von Willebrand factor (VWF) levels as well as analyzed the optimal clinical bleeding assessment tool (BAT) to evaluate bleeding. For this investigation, they assessed gynecological bleeding and directly compared the Condensed Molecular and Clinical Markers for the Diagnosis and Management of type 1 von Willebrand disease {VWD} (Condensed MCMDM-1 VWD) and International Society on Thrombosis and Haemostasis (ISTH) BAT scores in 120 women recruited in the Low von Willebrand in Ireland Cohort study. In women with low VWF, BATs differ significantly in sensitivity for detecting menorrhagia. In the result, they found that gynecological bleeding was frequently reported in women with low VWF. Findings revealed that significant postpartum hemorrhage (PPH) might occur in women with low VWF in spite of pregnancy-related increases in plasma VWF levels.