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Significance of intraparotid node metastasis in predicting local control in primary parotid cancer

The Laryngoscope Oct 06, 2019

Feng Y, et al. - In this investigation involving 337 patients, researchers analyzed the metastasis rate in intraglandular lymph nodes (IGLNs), focusing on the significance of IGLN metastasis in local control (LC) of parotid gland cancer (PGC). In 111 patients, IGLN metastasis was noted. IGLN metastasis was significantly related to tumor stage, pathologic nodal stage, perineural invasion, resection status, and lymphovascular invasion. In 67 patients, local recurrence was observed. An independent predictor of LC was IGLN metastasis. In PGC patients, the IGLN metastasis rate is relatively high and is significantly linked to disease grade and T stage. IGLN metastasis is correlated with poorer local LC, and the worst prognosis is for patients with more than two metastatic nodes.
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