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Shift work and the risk of coronary artery disease: A cardiac computed tomography angiography study

Cardiology Nov 04, 2017

Havakuk O, et al. - The burden of coronary artery disease (CAD) among shift workers and non-shift workers was compared in this study using cardiac computed tomography angiography (CCTA), and it was found that shift workers vs non-shift workers had a higher prevalence and extent of CAD.

Methods

  • This historically prospective study was performed in consecutive patients who underwent CCTA and answered a telephonic questionnaire.
  • Owing to significant differences in age and gender, researchers compared 89 well-matched pairs of shift workers and non-shift workers with the use of propensity scores.

Results

  • Overall, this analysis included 349 participants, of whom 94 (26.9%) were shift workers.
  • According to data, the mean age was 50.7 years, and 62.5% were males.
  • After pairing, it was evident that shift workers vs non-shift workers had a higher prevalence of CAD (74.2 vs. 53.9%, respectively, p=0.01), and a lower prevalence of coronary calcium scores of zero (46.8 vs. 63.4%, respectively, p=0.034).
  • In shift workers vs non-shift workers, stenosis >50% was more prevalent (20.2 vs. 11.2%, respectively, p=0.006), and a tendency for higher extent of CAD (defined as the presence of ≥1-vessel disease) was observed (25.8 vs. 13.5%, respectively, p=0.06).

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