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Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population

Journal of Child Psychology and Psychiatry Feb 24, 2018

Martin J, et al. - Researchers here tested two hypothesis: one suggesting that females with attention deficit hyperactivity disorder (ADHD) might be underdiagnosed or receive alternative diagnoses, such as anxiety or depression and; other suggesting that females might be protected from developing ADHD, requiring a higher burden of genetic risk to manifest the disorder. In this work, genetic evidence indicated that in females, ADHD risk may be more likely to manifest or be diagnosed as anxiety or depression than in males. The results did not support a higher ADHD genetic risk in females with ADHD as compared to affected males.
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