Ravn-Fischer A, Perers E, Karlsson T, et al. – In a cohort of 2,176 consecutive patients with acute coronary syndrome (ACS) who survived the first 30 days, researchers evaluated long-term mortality and its relation to baseline variables. Participants were observed for a median of 16 years 8 months. After adjusting for age, women vs men exhibited lower late mortality. Only men demonstrated increased long-term mortality in significant correlation with previous heart failure, previous or new-onset atrial fibrillation, and psychotropic drugs at discharge, as found upon using multivariable Cox regression. Factors that showed a significant relation to death only in women were: known hypertension, elevated creatinine, and in-hospital Killip class > 1/cardiogenic shock. A significant interaction of hypertension and in-hospital Killip class > 1/cardiogenic shock, with sex, was reported for late mortality. Considering sex-specific approaches for long-term follow-up of patients with ACS was recommended by the researchers.