Bjornstad P, et al. – Researchers evaluated the associations between serum uromodulin (SUMOD), coronary artery calcification (CAC) progression, and diabetic kidney disease (DKD) development over 12 years in this investigation. A total of 527 participants (53% females) in the Coronary Artery Calcification in Type 1 Diabetes (CACTI) study were examined in 2002–2004, at an average age of 39.6 ± 9.0 years and a median duration of diabetes of 24.8 years. In adults with type 1 diabetes, higher baseline SUMOD level predicted lower odds of both CAC progression and incident DKD over 12 years.