Chouri E, et al. - Levels of microRNAs (miRNAs) were assessed in the serum of systemic sclerosis (SSc) patients, as well as, their expression in early stages of the disease. Up-regulation of miR-483-5p was seen in the serum of SSc patients, from the early stages of the disease onwards. Additionally, its potential function as a fine regulator of fibrosis in SSc was also indicated.