Maurya RP, Prajapat MK, Singh VP, et al. - Researchers conducted this longitudinal cohort study to investigate the level of serum malondialdehyde (MDA), a biomarker of oxidative stress before and after chemotherapy in various ocular malignancies and to correlate its significance with clinicopathological parameters. Thirty-two histopathologically confirmed cases of primary ocular malignancies were involved in this analysis. The most common malignancy was eyelid malignancy (n=18, 56.2%) followed by retinoblastoma (18.8%) and OSSN (6, 18.8%). Sebaceous gland carcinoma of the eyelid was the most common malignancy. Serum MDA is a potential biomarker of primary ocular carcinoma for the assessment of oxidative stress and its impact on chemotherapy response.