Nam KW, et al. - In this analysis of a consecutive series of 3,145 neurologically healthy subjects recruited between January 2006 and December 2013, researchers assessed the association between serum gamma-glutamyl transferase (GGT) and the presence of silent brain infarcts (SBI). Brain magnetic resonance imaging was performed and GGT levels were assessed in participants. A total of 260 SBI cases were identified. Findings revealed higher SBI prevalence in association with increased serum GGT levels in a neurologically healthy population. Factors that were found to have significance for SBI, included age and hypertension. In the male group, these positive associations of GGT levels with SBI were more prominent, with a significantly increasing trend, as seen in a stratified analysis by sex. Female participants showed no association.