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Serum free testosterone and asthma, asthma hospitalisations and lung function in British adults

Thorax Sep 04, 2020

Han YY, Yan Q, Yang G, et al. - This cross-sectional study was undertaken to determine the association between serum-free testosterone and asthma, wheeze, asthma hospitalisations and lung function among older adults. This study was done in UK and involved adults (n = 256,419; aged 40 to 69 years) recruited from 2006 to 2010. Experts applied multivariable logistic or linear regression for evaluating free testosterone and physician-diagnosed asthma, current wheeze, asthma hospitalisations and lung function measures, which was adjusted for serum estradiol, smoking status and other covariates. Findings of this large study including British adults revealed that increased free testosterone levels were related to lower odds of asthma and current wheeze in females and males, lower odds of asthma hospitalisations in females, and higher FEV1 and FVC in males.

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