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Serum CXCL14 levels are associated with serum C‐peptide and fatty liver index in T2DM patients

Journal of Diabetes Investigation Oct 23, 2020

Matsushita Y, Hasegawa Y, Takebe N, et al. - Researchers investigated 176 patients with type 2 diabetes mellitus (T2DM), to examine the associations between serum C‐X‐C motif chemokine ligand 14 (CXCL14) levels and clinical parameters in these patients. Using ELISA, serum CXCL14 levels were ascertained. In patients suffering from T2DM, findings showed an independent link of serum CXCL14 levels with serum C‐peptide (CPR) and fatty liver index. Insulin resistance, rather than β‐cell function, may be reflected by a high serum CPR level in these patients, because CXCL14 displayed simple correlations with obesity‐associated parameters. Overall, experts concluded a likely usefulness of serum CXCL14 levels as predictors of increased serum CPR and hepatic steatosis in patients with T2DM.

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