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Semen impairment and occurrence of SARS-CoV-2 virus in semen after recovery from COVID-19

Human Reproduction Feb 04, 2021

Gacci M, Coppi M, Baldi E, et al. - Researchers examined the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the semen quality of recovered sexually active men. They conducted a prospective cross-sectional study including 43 sexually active men who were identified to have recovered from SARS-CoV2. All individuals were administered questionnaires including International Index of Erectile Function and Male Sexual Health Questionnaire Short Form. All the biological fluids obtained were assessed for the occurrence of virus RNA by RT-PCR. Evaluation of semen parameters was done according to the World Health Organization manual edition V. Two-step ELISA method was used to evaluate semen IL-8 levels. Findings suggest that 25% of the men with recent SARS-Cov-2 infections and proven healing were oligo-crypto-azoospermic, despite no detection of virus RNA in semen.

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