Andrei F, Salvatori P, Cipriani L, et al. - Researchers aimed at comparing women and men who were clinically diagnosed with an anatomical cause of infertility or non-anatomical cause of infertility, with respect to the magnitude and the predictors of emotional reactions to an infertility diagnosis. Among 133 adults waiting for infertility treatment in this cross-sectional study, they identified 107 patients (55 with anatomical causes of infertility and 52 with non-anatomical causes of infertility; response rate: 80%) for participation in this study. Statistically significant lower scores were recorded for women vs men on the Infertility Self-Efficacy Scale and on the global, emotional, and mind-body subscales of the Fertility Quality of Life, while significantly higher scores were recorded for women on the emotion focused and socially supported subscales of the Coping Orientation to Problem Experienced. This study, in part, provide validation to the data on gender disparities in experiencing the psychological burden of infertility and adds some new information, particularly with respect to the prediction of quality of life indicators over and above infertility cause. .