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Salidroside protects against MPP+-induced neuronal injury through DJ-1-Nrf2 antioxidant pathway

Evidence-based Complementary and Alternative Medicine Oct 07, 2017

Wu L, et al. - In this work, researchers investigated the molecular mechanism responsible for neuroprotective effects exhibited by salidroside (Sal) against MPP+ toxicity. As per findings, they conclude that Sal prevented MPP+-induced neurotoxicity through upregulation of DJ-1-Nrf2-antioxidant pathway. Novel insights into the neuroprotective effects of Sal against PD were provided by the findings.
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