Zhou Y, et al. – Aim of this study was to hypothesize understanding the correlations between fat mass– and obesity–associated (FTO) rs9939609 with FTO methylation and telomere length will provide a more accurate assessment of obesity risk. FTO rs9939609 is correlated with obesity risk and LTL in this study, where this correlation is only found at higher, but not lower, FTO methylation levels of participants. The outcomes validate the correlation of multiple factors, including FTO methylation level, may be involved in one of several mechanisms underlying the commonly reported obesity risk of this FTO polymorphism.