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Role of prenatal magnetic resonance imaging in fetuses with isolated anomalies of the corpus callosum: A multinational study

Ultrasound in Obstetrics & Gynecology Feb 20, 2021

D’Antonio F, et al. - In this multicentre, retrospective, cohort study involving 14 fetal medicine centres in Italy, United Kingdom, Portugal, Canada, Austria and Spain, researchers sought to evaluate the role of fetal MRI in detecting associated anomalies in fetuses presenting with isolated corpus callosum (CC) anomalies at multiplanar ultrasound (US) evaluation of fetal brain (neurosonography). Two‐hundred and sixty‐nine fetuses with a sonographic prenatal diagnosis of apparently isolated CC anomalies [207 with complete, (cACC) and 62 with partial (pACC)], were involved in the investigation. MRI can identify a small proportion of additional anomalies in fetuses with isolated CC anomalies diagnosed during antenatal neurosonography, mainly cortical developmental malformations, which are not detected by ultrasound.

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