Wehner MR, Niu J, Wheless L, et al. - Among organ transplant recipients (OTRs) who developed at least 1 posttransplant skin cancer, the occurrence of a subsequent skin cancer within 2 years was evident in nearly half of them, and approximately 1 in 20 developed 10 or more skin cancers. Thus, diligent dermatology follow-up is important.

• This retrospective cohort study utilizes data (2007 to 2017) from Optum (an electronic health record data set) and MarketScan (a claims data set).

• From these datasets, 7390 and 133 651 OTRs were identified, respectively, 4.5% and 13.3% of which had received at least 1 skin cancer treatment, respectively.

• At 2 years following the initial posttransplant skin cancer in the data sets, OTRs were found to have a 44.0% to 57.0% risk of a subsequent skin cancer treatment and a 3.7% to 6.6% risk of having 10 or more skin cancer treatments.

• In both data sets, age, history of skin cancer, and history of actinic keratosis were revealed as statistically significant risk factors for any skin cancer, such factors were male gender and thoracic transplant in MarketScan.