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Risk of stroke in patients with ocular arterial occlusive disorders: A retrospective Canadian study

Journal of the American Heart Association Feb 08, 2019

Avery MB, et al. - In this retrospective cohort study, researchers examined the association between monocular vision loss, attributed to either central retinal artery occlusion (CRAO), branch retinal artery occlusion (BRAO), or ocular ischemic syndrome (OIS) and the importance of related internal carotid artery stenosis in clinical decision making. Participants were patients who initially presented with CRAO, BRAO, or OIS to a centralized ophthalmology center in Canada over a 5-year period and were followed for 3 years for the occurrence of a hemispheric stroke. They identified 83 affected eyes, with 31 CRAO, 35 BRAO, and 17 OIS patients. A symptomatic stroke occurred in 32.3%, 11.4%, and 41.2% of CRAO, BRAO, and OIS patients, respectively, prior to ocular diagnosis. Significantly increased symptomatic stroke rates were reported in association with CRAO, BRAO, and OIS. For risk stratification in these patients, the degree of ipsilateral internal carotid artery stenosis may not have any utility. This led to the recommendation for triaging these patients appropriately for stroke risk-factor management, independent of internal carotid artery stenosis.

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