Mroueh R, et al. - Since a rise in the incidence as well as the survival of oral squamous cell carcinoma (OSCC) patients has been seen in recent years, and it is important to understand long-term survival aspects in order to ensure optimal treatment and follow-up planning, and given about one in five cancers diagnosed occurs nowadays in people with a prior diagnosis of cancer, so, researchers undertook this inquiry using the Finnish Cancer Registry among patients who received a diagnosis of primary OSCC during 1953-2015. Compared with the general population, both standardized incidence ratios (SIR) and excess absolute risk (EAR) per 1000 person-years at risk of second primary cancer (SPC) were estimated. This study included 6,602 first primary OSCC patients with 640 (10%) SPCs. The estimated SIR for SPCs was 1.85 corresponding to an EAR of 8.78. Experts concluded that awareness regarding the second primary cancer risk following treatment of primary OSCC should exist among health care professionals and patients should be counseled regarding this phenomenon.