Risk of ascending aortic aneurysm in patients with autosomal dominant polycystic kidney disease
The American Journal of Cardiology Nov 10, 2018
Bouleti C, et al. - The paucity of data on aortic dilation in patients with autosomal dominant polycystic kidney disease (ADPKD) led researchers to compare sinuses of Valsalva (SoV) and tubular ascending aorta diameters in ADPKD patients with matched controls. Specifically, participants were 61 consecutive ADPKD patients who had an echocardiogram done. These patients were matched 1:1 with controls for sex, age, blood pressure and beta-blocker therapy use. The mean age of patients was 56±12 years. Among all the participants, 54% were men. Beta-blockers were received by 38%. Findings revealed that, ADPKD patients vs controls matched for common confounding factors for aortic dilation had an increased prevalence of aortic aneurysms.
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