Wang N, et al. - Considering recent research indicates higher mortality among elderly patients with upper gastrointestinal hemorrhage (UGH) complicated with acute coronary syndrome (ACS) vs a single UGH, researchers sought the risk factors linked with an increased risk of ACS occurrence following UGH. The hospital information system database of Shengjing Hospital of China Medical University was analyzed to conduct this population-based nested case-control study. Among 3,217 elderly patients who experienced a UGH, they found 152 cases and matched them to 604 selected controls. As per findings, risk factors to develop ACS in elderly patients with UGH were history of diabetes, vasopressin or terlipressin use, smoking, liver cirrhosis, hemoglobin level, and history of ACS. Importantly, key variables for mortality were diabetes, smoking, and lower hemoglobin level.