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Risk factors for medication non-adherence among atrial fibrillation patients

BMC Cardiovascular Disorders Feb 17, 2019

Reading SR, et al. - Via analyzing data from a large, ethnically-diverse cohort of Kaiser Permanente Northern and Southern California adult members with incident atrial fibrillation (AF) between January 1, 2006 and June 30, 2009, researchers investigated risk factors for general medication non-adherence. The definition of medication non-adherence was either taking medication(s) as the doctor prescribed ≤ 75% of the time, or forgetting or opting to skip ≥ 1 medication(s) at least once per week. Factors related to higher adjusted odds of non-adherence included minority race/ethnicity vs non-Hispanic white, not married/with partner vs married/with partner, physical inactivity vs physically active, alcohol use vs no alcohol use, any days of self-reported poor physical health, mental health and/or sleep quality in the past 30 days vs 0 days, memory decline vs no memory decline, inadequate vs adequate health literacy, low-dose aspirin use vs no low-dose aspirin use, and diabetes mellitus. Lower adjusted odds of non-adherence were reported in relation to ages 65–84 years vs < 65 years of age, a Charlson Comorbidity Index score ≥ 3 vs 0, and hypertension.

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