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Reossification and prognosis following radiotherapy with/without surgery for spinal solitary plasmacytoma of the bone: A retrospective study of 39 patients

The Spine Journal Oct 28, 2019

Ouyang H, Han S, Jiang L, et al. - In this retrospective observational study of individuals who had spinal solitary plasmacytoma of bone (SPB) and who got radiotherapy with/without surgery, without chemotherapy, denosumab or zoledronic acid, researchers assessed reossification following radiotherapy and prognostic factors of spinal SPB using single-center data. Twenty-six men and 13 women were involved. In individuals with spinal SPB, 41.0% of lesions exhibited important reossification following radiotherapy. A superior prognosis with less likelihood of multiple myeloma progression was seen in individuals with notable reossification. Thus, for spinal SPB, radiotherapy could be a safe and efficient treatment option, although, more attention should be given to reossification.
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