Damianaki K, Lourenco JM, Braconnier P, et al. - Researchers investigated if zinc deficiency was associated with raised renal excretion of zinc and with the progression of chronic kidney disease (CKD). This study involved 108 CKD patients and 81 persons without CKD. Among participants, measurements of plasma and 24-h urinary zinc levels, urinary electrolytes and uromodulin were obtained. Experts found that CKD patients had lower zinc levels, which were not compensated by decreased renal zinc excretion. An impaired tubular activity, likely suggested by an inverse link between urinary zinc excretion and uromodulin, could partly account for zinc imbalance in CKD. As per the findings, zinc status was related to renal function decline.