Koizumi M, Ida S, Shoji Y, et al. - Risk of renal dysfunction is reported to be higher among children born small for gestational age (SGA), particularly when associated with an extremely low birthweight (ELBW). Short-statured children born SGA are provided growth hormone (GH) treatment; researchers herein investigated its effects on renal function, especially in those born SGA with ELBW. They subdivided short-statured children born SGA (N = 42) into two groups based on their birthweight: the ELBW group (N = 15) with a birthweight of < 1,000 g, and the non-ELBW group (N = 27) with birthweights ranging between 1,000 and 2,500 g. Comparing the creatinine-based estimated glomerular filtration rates (eGFR) before (pre-eGFR) and 5 years after GH treatment (post-eGFR), they did not identify GH treatment to be a risk factor for the reduction in eGFR in short-statured children born SGA. However, careful monitoring of eGFR is recommended, especially in those born SGA with ELBW, as these individuals had lower eGFR than non-ELBW individuals.