• Profile

Relative efficacy of minoxidil and the 5-α reductase inhibitors in androgenetic alopecia treatment

JAMA Feb 05, 2022

The observations from this meta-analysis add to the comparative effectiveness literature for androgenetic alopecia (AGA) therapies with regard to the compared interventions.

  • The relative efficacy of monotherapy with orally and topically administered minoxidil, dutasteride, and finasteride for male AGA was assessed.

  • This network meta-analysis of 23 trials was conducted to determine the rank of efficacy across treatments and the relative efficacy for every possible pairwise comparison of treatments for 4 endpoints (ie, change in total and terminal hair count after 24 and 48 weeks).

  • According to findings, the highest probability of being the most efficacious therapy was shown by 5 mg/d of oral dutasteride, followed by these agents in decreasing order of efficacy: 5 mg/d of oral finasteride, 5 mg/d of oral minoxidil, 1 mg/d of oral finasteride, 5% topical minoxidil, 2% topical minoxidil, and 0.25 mg/d of oral minoxidil.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
M3 app logo
Choose easy access to M3 India from your mobile!

M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen