Hansen GM, Jørgensen PG, Andersen HU, et al. - In this observational cohort study involving 946 patients (51.5% men) with type 1 diabetes (T1DM) and no known cardiovascular disease (CVD), researchers sought to explore the connection between measures of peripheral neuropathy (PN) and impaired left ventricular diastolic function. They also assessed their prognosis and the incremental prognostic value of including measures of PN and diastolic function to the established Steno T1 Risk Engine. In order to assess diastolic function and PN, echocardiography and quantitative biothesiometry were conducted. A higher risk of CV events and all-cause mortality in T1DM patients is associated with peripheral neuropathy and impaired diastolic function. Measures of diastolic function enhanced prognosis prediction by the Steno T1 Risk Engine.