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Relation of obesity to outcomes of hospitalizations for atrial fibrillation

The American Journal of Cardiology Feb 21, 2019

Agarwal MA, et al. – Given that the impact of obesity on outcomes of hospitalizations for atrial fibrillation (AF) remains unclear, researchers analyzed the National Inpatient Sample (NIS) database 2010-2014 in order to assess all adult hospitalizations with a primary diagnosis of AF. They identified obese patients using the comorbidity variable for obesity (per the NIS databases). Via multivariable logistic regression, they compared in-hospital outcomes (eg, mortality and acute stroke events) between obese and non-obese patients with AF. Compared with non-obese patients, obese patients were younger and more frequently African Americans. They noted a higher prevalence of cardiovascular comorbidities like hypertension, diabetes mellitus, dyslipidemia, smoking, heart failure, and chronic renal failure in obese patients. Overall, however, they observed lower in-hospital mortality and acute stroke events among obese patients, after multivariate risk adjustment.

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