Rhee H, Berenger B, Mehta RL, et al. - This retrospective cohort analysis was conducted to determine the results of RCA-CKRT [RCA (regional citrate anticoagulation) for CKRT (continuous kidney replacement therapy)] using calcium-containing solutions. Investigators assessed the safety as well as the efficacy of RCA-CKRT with calcium-containing dialysate and replacement fluid used for 128 patients. They assessed 571 filters and 1,227 days of CKRT. Most of the participants were male 91 (71.1%), liver disease was present in 32 (25%), and sepsis without liver disease in 29 (22.7%). A decrease in intravenous calcium needs by 31.7% was brought about by calcium-containing replacement solutions. Findings demonstrated feasibility as well as safety of RCA-CKRT with calcium-containing solutions among critically ill patients including those suffering from sepsis and liver disease.