Zheng LJ, Jiang W, Pan L, et al. - The results showed that hypoalbuminemia is correlated with poor prognosis in critically ill acute kidney injury patients with continuous renal replacement therapy; thus, assessing albumin may be beneficial for predicting the prognosis. Nevertheless, this conclusion is not valid in those with oliguria.

• Researchers recruited a total of 837 patients in this study.

• In the Multivariate Cox proportional hazard regression analysis, findings indicated that hypoalbuminemia was correlated with both 28-day and 90-day mortality risks after full adjustment for confounding variables, with an adjusted hazard ratio (95% confidence interval) of 0.63 (0.50–0.80) and 0.63 (0.51–0.78), respectively for each 1 g/dL increase of albumin.

• The stratified analysis demonstrated that hypoalbuminemia was not correlated with poor prognosis in oliguria.