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Real‐world evidence of age‐independent electroconvulsive therapy efficacy: A retrospective cohort study

Acta Psychiatrica Scandinavica Nov 02, 2021

Luccarelli J, McCoy TH, Seiner SJ, et al. - A retrospective cohort study examining the effects of electroconvulsive therapy (ECT) on depression and cognition.

  • Researchers assessed a total of 1,698 patients who were receiving ECT and were evaluated with the Quick Inventory of Depressive Symptomatology (QIDS), the Behavior and Symptom Identification Scale-24 (BASIS-24), and the Montreal Cognitive Assessment (MoCA) at baseline and after treatment #10.

  • There appeared improvement in depression and overall self-reported mental health, with a slight reduction in cognition, in correlation with undergoing ECT.

  • No association of age was observed with changes in efficacy, however, older age was linked with a lesser cognitive change as assessed by the MoCA.

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