Madi M, et al. - Herein, the authors carried out a systemic review to assess the possible surgical treatment modalities for induced peri-implantitis to regain re-osseointegration. They observed promising results in the studies that used combination of bone substitutes together with guided bone regeneration for the regenerative therapy. Regarding the implant surfaces, with rough implant surfaces rather than smooth ones, a better re-osseointegration was seen.