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Randomized trial of the i-gel supraglottic airway device vs tracheal intubation during out of hospital cardiac arrest (AIRWAYS-2): Patient outcomes at 3 and 6 months

Resuscitation Oct 07, 2020

Benger JR, Lazaroo MJ, Clout M, et al. - In the AIRWAYS-2 cluster randomized controlled trial, the i-gel supraglottic airway device (SGA) was compared with tracheal intubation (TI) as the first advanced airway management (AAM) strategy used by Emergency Medical Service clinicians (paramedics) managing adult patients with non-traumatic out-of-hospital cardiac arrest (OHCA). The primary outcome of modified Rankin Scale (mRS) score at 30 days/hospital discharge did not differ between the two groups. In this paper, outcomes to 6 months are reported. Randomization of paramedics from four ambulance services in England to use an i-gel SGA (759 paramedics) or TI (764 paramedics) as their initial approach to AAM was performed. Survival to 30 days/hospital discharge was observed in 767 of 9,296 (8.3%) enrolled patients; of 767 survivors, 317 (41.3%) consented and were followed-up to 6 months. Outcomes indicated that the TI and i-gel groups had no statistically significant differences at 3 and 6 months. Hence, the initially inscribed finding of no significant difference between groups at 30 days/hospital discharge was sustained when the duration of follow-up was extended to 6 months.

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