Montenegro MM, et al. - In this single-blind, parallel design, randomized controlled trial, researchers examined 82 candidates of mean age 59.6 years to estimate the influence of periodontal therapy (PT) on cardiovascular blood biomarkers. They observed a significant rise in C reactive protein (CRP) in the control group (CG) (1.44±0.82mg/L to 4.35±7.85mg/L) and no change in CRP in the test group (TG) (1.40±0.96mg/L to 1.33±1.26mg/L), resulting in a significant difference between groups at 3 months. A significant decrease in CRP was noted only in TG (11.3±12.8mg/L to 5.7±4.1mg/L) among subjects with CRP ≥3mg/L. They also found lower levels of IL-6 and IL-8 in TG at 3 months.