Baskovic M, et al. - Researchers used the California Cancer Registry database (CCR), to determine the factors influencing overall prognosis and survival among different racial groups diagnosed with high-grade endometrial cancer (EC). They examined a cohort of patients of high-grade EC, with predominance of non-Hispanic (NH) white (64.1%), followed by Hispanic (15.7%), Asian (10.4%), and NH black (9.8%). The estimated five-year disease-specific survival (DSS) for NH black women was 54%, vs NH white women 66%, Hispanic 67%, and Asians 69%. A higher incidence of more aggressive histologic subtypes was reported among NH black women, even among a cohort of women high-grade EC. Furthermore, non-Hispanic black women showed disproportionately worse disease-specific survival after controlling for factors such as age, histologic subtype, stage, time to treatment, and type of treatment.