Zaghlol R, et al. - Researchers performed this study with a large national sample of people with Takotsubo cardiomyopathy (TC), to determine how race influences in‐hospital outcomes of these patients. From the National Inpatient Sample database, TC hospitalizations from 2006 to 2014 were selected and included in a US‐wide analysis. To decrease the selection bias, they eliminated cases with a primary diagnosis of acute coronary syndrome. Disparities in baseline features and in‐hospital outcomes were compared between Caucasians and African Americans (AA). A significant rise in the annual number of TC hospitalizations was reported in both races from 2006 to 2014. An initial increment in in‐hospital mortality was noted which was subsequently continued to be relatively stable around 5–7% with no significant variation between races. This work affords the first large US‐wide inquiry for racial disparities in TC outcomes. More in‐hospital complications were reported in AA overall; however, the disparities were driven by racial variations in demographics, comorbidities, and socio‐economic factors.