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R-CHOP, radioimmunotherapy, and maintenance rituximab in untreated follicular lymphoma (SWOG S0801): A single-arm, phase 2, multicentre study

The Lancet Haematology Jan 31, 2018

Barr PM, et al. - This trial was formulated in order to gauge the efficacy and safety of consolidative radioimmunotherapy and sequential maintenance rituximab following chemoimmunotherapy in advanced-stage follicular lymphoma. Data disclosed near universal responses following chemoimmunotherapy and radioimmunotherapy. The occurrence of maximum discontinuations during maintenance therapy indicated that rituximab over a 4-year span was not feasible for several patients. Nevertheless, this sequential therapeutic strategy led to good overall outcomes for patients, with the inclusion of a low incidence of early disease progression.
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