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Quantitative assessment of the effect of fasting on macular microcirculation: An optical coherence tomography angiography study

British Journal of Ophthalmology Nov 08, 2019

Karaküçük Y, et al. - Researchers examined how fasting influences the retinal vascular plexus and choriocapillaris structures in healthy individuals using optical coherence tomography angiography (OCTA). The OCTA scans of 98 eyes in 49 healthy individuals in fasting vs non-fasting period were compared for this work. Full ophthalmological examination was done in cases, with OCTA parameters measured, including superficial flow area (SCP), deep flow area (DCP), choriocapillaris flow area (CC), superficial and deep vascular density, superficial foveal avascular zone area, deep foveal avascular zone area, subfoveal choroidal thickness (SFCT) and central macular thickness. They reported significantly lower mean values for the SCP, DCP and CC flow area in a fasting than a non-fasting period. The mean vascular density was statistically significantly lower in a fasting period than in a non-fasting period at the SCP level. During a fasting period, statistically significant and thicker SFCT was reported.
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