Wohlfahrt P, Nativi-Nicolau J, Zhang M, et al. - Health-related quality of life of HFrEF (heart failure and reduced ejection fraction) patients improved significantly in relation to normalization of left ventricular systolic function.

• A prospective cohort study performed at a tertiary care hospital.

• Of 319 patients (mean [SD] age, 60.4 [15.5] years); 212 (66.5%) had HFrEF and 107 (33.5%) had heart failure with preserved ejection fraction at baseline.

• Significant improvement in health-related quality of life was seen in HFrEF cases with left ventricular ejection fraction recovery to 50% or more over a 1-year follow-up.

• A mean increase of 4.8 points on the Kansas City Cardiomyopathy Questionnaire summary score was observed with each 10% improvement in left ventricular ejection fraction.