Darma S, et al. - Via spectral domain optical coherence tomography (SD-OCT) (Topcon 3DOCT-2000) volume scans of the optic disc of 13 right eyes of cataract patients, the researchers corrected peripapillary retinal nerve fiber layer (pRNFL) measurements achieved with SD-OCT for low image quality factor (QF) using measurements pre- and post-cataract surgery. A significant difference in pRNFL thickness measurements before and after the cataract was observed. Corrected pRNFL thickness measurements pre-cataract surgery varied significantly with pRNFL thickness measurements post-cataract surgery. Hence, the presence of cataract affected the QF-pRNFL relationship. Image QF and pRNFL thickness underestimation were noted inversely proportional to one another which was somewhat a curvilinear relationship. Furthermore, after cataract surgery, corrected measurements of the pRNFL thickness in the case of lower image QF due to cataract were still significantly distinctive from the pRNFL thickness measurements.