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Qualitative evaluation of neuroretinal rim and retinal nerve fibre layer on optical coherence tomography to detect glaucomatous damage

British Journal of Ophthalmology Nov 08, 2019

Wu Z, Vianna JR, Reis ASC, et al. - Researchers examined if Bruch’s membrane opening-minimum rim width (BMO-MRW) measurements improve the efficacy of conventional circumpapillary retinal nerve fibre layer (cpRNFL) thickness measurements on optical coherence tomography (OCT) imaging for discriminating between perimetric glaucoma and healthy eyes, evaluated through a qualitative evaluation. They performed an evaluation of 384 healthy eyes and 188 glaucoma eyes, and categorization of glaucoma eyes as perimetric (n = 107) based on a history of ≥ 3 consecutive abnormal 24–2 visual field tests or suspected glaucoma if they did not (n = 81). Two experienced graders qualitatively evaluated OCT-derived BMO-MRW and cpRNFL reports in isolation at first, and then by using both reports combined. Findings revealed that no difference was exhibited by the experienced graders in discriminating between perimetric glaucoma and healthy eyes when using a cpRNFL report alone, the BMO-MRW report alone or the two reports combined. This suggests the utility of using either OCT imaging report of the neuroretinal tissue for effectively detecting perimetric glaucoma.
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