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Psoriasis-related treatment exposure and hospitalization or in-hospital mortality due to COVID-19 during the first and second wave of the pandemic: Cohort study of 1,326,312 patients in France

British Journal of Dermatology Sep 04, 2021

Penso L, Dray-Spira R, Weill A, et al. - It was shown that systemic treatments for psoriasis (including biologics) were not correlated with an elevated risk of in-hospital mortality due to COVID-19. During the pandemic, data support maintaining systemic treatment for psoriasis.

  • Researchers distinguished 1,326,312 patients with psoriasis (mean age 59 years; males, 48%).

  • Furthermore, 3871 patients were hospitalized for COVID-19 and 759 (20%) died during the first study period, while 3603 were hospitalized for COVID-19 and 686 (19%) died during the second period.

  • The risk of hospitalization for COVID-19 was associated with exposure to topicals or nonbiologic [hazard ratio (95% confidence interval): 1·11 (1·04–1·20) and 1·27 (1·09–1·48), respectively] during the first period, and with all exposure types, during the second period in the propensity score-weighted Cox models.

  • Due to COVID-19, none of the exposure types was correlated with in-hospital mortality.

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