• Profile
Close

Pruritus-reducing effects of omega-3 fatty acids in hemodialysis patients: A cross-over randomized clinical trial

Hemodialysis International Feb 05, 2022

Investigating omega-3 supplementary intake as an intervention to treat chronic kidney disease-associated pruritus, this study revealed decreasing effects of omega-3 fatty acids (3 grams per day) on pruritus. Decrease in prostaglandin E2 levels in the omega-3 group did not differ from the changes in the placebo group.

  • In this double-blinded, randomized, crossover study, 40 hemodialysis patients with pruritus were randomized into two groups (Group A and Group B).

  • Patients in Group A were asked to consume omega-3 capsules for 4 weeks and after a washout period (6 weeks), they were administered placebo for another 4 weeks; the same was done in Group B but in the reverse order.

  • Patients after receiving omega-3 fatty acid supplement exhibited a statistically significant reduction of pruritus score.

  • Significant reduction in the mean pruritus score was evident in both first and second treatment period after omega-3 intake; however no significant mean pruritus score difference was observed in the placebo group after both intervention periods.

  • In the intervention (omega-3) group, reduction in prostaglandin E2 amount was not statistically significant relative to the placebo group.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay