Villavicencio AT, Nelson L, Rajpal S, et al. - A prospective, randomized, double-blinded clinical trial was conducted to explore clinical and radiological outcomes in patients undergoing lumbar interbody fusions and randomized to receive either polyether-ether-ketone (PEEK) or structural bone allografts. A sum of 138 patients were included, assigned randomly and 121 patients completed the study. Researchers recruited a total of 138 patients who had undergone transforaminal lumbar interbody fusions (TLIF). Individuals were assigned randomly in a 1:1 to receive either cortical allograft or PEEK interbody lordotic spacers. The results showed that TLIF surgery with two different types of cages and in conjunction with rhBMP-2 resulted in similar radiological or clinical outcomes and a highly statistically significant improvement in all clinical outcome measures at the end of the study regardless of the randomization group, although allograft-assisted surgeries may have reduced fusion rates.