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Prospective evaluation of the comorbidity of obstructive sleep apnea in patients with glaucoma

Journal of Clinical Sleep Medicine Jun 29, 2021

Chan YH, Chuang LH, Yu CC, et al. - Researchers sought to prospectively identify the association between obstructive sleep apnea (OSA) severity, ocular microcirculation changes, and visual function changes in patients with glaucoma. Patients with glaucoma who were willing to undergo overnight polysomnography (PSG) were included prospectively. Patients were separated into three groups: normal tension glaucoma (NTG), high-tension glaucoma (HTG), and control. Using sequential standard automated perimetry, visual field (VF) progression was analyzed. The connections between PSG parameters, OCT-Angiography parameters, and VF progression have been analyzed. In total, 22 patients with NTG, 30 patients with HTG, and 24 control patients were recruited. When compared with the control group, having glaucoma raised the incidence of moderate-to-severe OSA. In patients with glaucoma, OSA severity was correlated with VF worsening, which was then related to a structural progression in the NTG subgroup. To prevent disease progression, patients with glaucoma must have their comorbid OSA status carefully monitored.

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