Brouillette MJ, et al. - Given a common occurrence of mild cognitive impairment in chronic HIV infection and concerns regarding it worsening with age, researchers assessed the degree of change after administering three different forms of a brief computerized cognitive assessment battery (B-CAM) developed to measure cognitive ability in people living with HIV in the mildly-impaired to normal range. Assuming that no change over a six-month period would occur in people on effective antiretroviral therapy, they had 102 HIV+ individuals complete a set of computerized cognitive tasks on three occasions over a six-month period. They used Rasch analysis to ascertain uniformity in change over time (ie improvement due to practice) across tasks and to refine scoring in order to produce three forms of the B-CAM of equivalent level of difficulty. The three forms of the B-CAM are of equivalent difficulty, as per Rasch analysis mathematical measures. As per Group-based trajectory analysis, there appeared no need to adjust the total score to correct for practice effects. Quick and robust quantification of change in cognition seems possible with these modern statistical methods.